To date, driver genes for pancreatic cancer treatment are difficult to pursue therapeutically.Targeting mutated KRAS, the most renowned driver gene in pancreatic cancer, is an active area of study.We discovered a gene named SEMA3C was highly expressed in pancreatic cancer cell lines and patients with a G12D mutation in KRAS.High expression of SEMA3
Advance in Silicon Photomultiplier for All-Digital Positron Emission Tomography
In recent years, silicon photomultipliers (SiPMs) have emerged as preferred photoelectric conversion devices in positron emission tomography (PET) due to their outstanding performance.SiPMs possess single-photon resolution capability and time resolution below 100 ps, enabling precise photon arrival time measurements.These advances paved the way Sto
On Covariance Matrix Based Spectrum Sensing Over Frequency-Selective Channels
This Battery Back Up paper concerns covariance matrix-based spectrum sensing over frequency-selective channels.The impact of frequency-selective channels on the covariance matrix of received signals is analyzed in frequency domain, and it is shown that the phases of channel spectra degrade the performance of covariance matrix-based detectors.To ove
Monitoring Dynamic Changes of Cellular Membrane GSH During Stroke via an ESIPT-Based Near-Infrared Fluorescent Probe
Stroke, primarily ischemic (85%), results from inadequate blood supply and is worsened by ferroptosis, characterized by free radical generation Vacuum Cloth Filter and lipid peroxidation.Monitoring ferroptosis is essential for understanding its mechanisms and developing treatments.Glutathione (GSH) is a key ferroptosis biomarker, but current probes
Gut microbiota determines the social behavior of mice and induces metabolic and inflammatory changes in their adipose tissue
Abstract The link between the gut microbiota and social behavior has been demonstrated, however the translational impact of a certain microbiota composition on stable behavioral patterns is yet to be elucidated.Here we employed an established social behavior mouse model of dominance (Dom) or submissiveness (Sub).A comprehensive 16S rRNA gene sequen